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Index > Protein center > Ghr(Gene name) > Mouse
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  • Ghr (Gene name),
  • Growth hormone receptor (Protein name ),  GHR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Ghr;
    Protein name:
    Growth hormone receptor(GH receptor);
    Alternative:
    Somatotropin receptor;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
    Function:
    The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    650
    Sequence:
    50:
    MDLCQVFLTL | ALAVTSSTFS | GSEATPATLG | KASPVLQRIN | PSLGTSSSGK | 
    100:
    PRFTKCRSPE | LETFSCYWTE | GDNPDLKTPG | SIQLYYAKRE | SQRQAARIAH | 
    150:
    EWTQEWKECP | DYVSAGKNSC | YFNSSYTSIW | IPYCIKLTTN | GDLLDQKCFT | 
    200:
    VDEIVQPDPP | IGLNWTLLNI | SLTGIRGDIQ | VSWQPPPNAD | VLKGWIILEY | 
    250:
    EIQYKEVNES | KWKVMGPIWL | TYCPVYSLRM | DKEHEVRVRS | RQRSFEKYSE | 
    300:
    FSEVLRVIFP | QTNILEACEE | DIQFPWFLII | IFGIFGVAVM | LFVVIFSKQQ | 
    350:
    RIKMLILPPV | PVPKIKGIDP | DLLKEGKLEE | VNTILGIHDN | YKPDFYNDDS | 
    400:
    WVEFIELDID | EADVDEKTEG | SDTDRLLSND | HEKSAGILGA | KDDDSGRTSC | 
    450:
    YDPDILDTDF | HTSDMCDGTL | KFRQSQKLNM | EADLLCLDQK | NLKNLPYDAS | 
    500:
    LGSLHPSITQ | TVEENKPQPL | LSSETEATHQ | LASTPMSNPT | SLANIDFYAQ | 
    550:
    VSDITPAGGD | VLSPGQKIKA | GIAQGNTQRE | VATPCQENYS | MNSAYFCESD | 
    600:
    AKKCIAVARR | MEATSCIKPS | FNQEDIYITT | ESLTTTAQMS | ETADIAPDAE | 
    650:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036d
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    MSDS:
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    96T
    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse GH receptor
    MSDS:
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    ELISA Kit for Mouse GH receptor
    Cat.:
    E1036b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036d
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GH receptor
    Cat.:
    U1036h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Mouse GH receptor
    MSDS:
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    Polyclonal Antibody for Mouse GH receptor
    Cat.:
    P1036Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GH receptor
    Cat.:
    P1036Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GH receptor
    Polyclonal Antibody for Mouse GH receptor
    Cat.:
    P1036Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GH receptor
    Polyclonal Antibody for Mouse GH receptor
    Polyclonal Antibody for Mouse GH receptor
    Polyclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Monoclonal Antibody for Mouse GH receptor
    Protein for Mouse GH receptor
    Cat.:
    R1036h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor
    Protein for Mouse GH receptor

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    References
    1. 1.
      "Mouse serum growth hormone (GH) binding protein has GH receptor extracellular and substituted transmembrane domains."
      Smith W.C. , Kuniyoshi J. , Talamantes F.
      Mol. Endocrinol.3:984-990(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    2. 2.
      "Mouse growth hormone receptor/binding protein and growth hormone receptor transcripts are produced from a single gene by alternative splicing."
      Edens A. , Southard J.N. , Talamantes F.
      Endocrinology135:2802-2805(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE OF 156-300 (ISOFORM 1)
      strain: DBA/2J.
      strain: Swiss Webster.
    3. 3.
      "Structure and expression of the mouse growth hormone receptor/growth hormone binding protein gene."
      Moffat J.G. , Edens A. , Talamantes F.
      J. Mol. Endocrinol.23:33-44(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1 AND 2)
      strain: DBA/2J.
      strain: Swiss Webster.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Kidney.
    5. 5.
      "An exon encoding the mouse growth hormone binding protein (mGHBP) carboxy terminus is located between exon 7 and 8 of the mouse growth hormone receptor gene."
      Zhou Y. , He L. , Kopchick J.J.
      Receptor4:223-227(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 47-88 AND 156-650 (ISOFORM 1)
      strain: C57BL/6.
    6. 6.
      Zhou Y. , He L. , Kopchick J.J.
      Submitted (1996-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    7. 7.
      "Mouse growth hormone receptor cytoplasmic exons 9 and 10 genomic clone with flanking intronic sequence."
      Rowland J.E. , Waters M.J.
      Submitted (2003-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 302-650 (ISOFORM 1)
      strain: 129/SvJ.
    8. 8.
      "Isolation of two molecular weight variants of the mouse growth hormone receptor."
      Smith W.C. , Colosi P. , Talamantes F.
      Mol. Endocrinol.2:108-116(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-41
    9. 9.
      "Structure and regulation of expression of the mouse GH receptor."
      Talamantes F. , Ortiz R.
      J. Endocrinol.175:55-59(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
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